HAD

Generic Name: benzocaine (Oral route, Oromucosal route)

BEN-zoe-kane

Commonly used brand name(s)

In the U.S.

• Anbesol


• Babee Teething


• Benzodent


• Benz-O-Sthetic


• Bi-Zets/Benzo-Troches


• Dentemp's


• Dent-O-Kain/20


• Detane


• Gumsol


• HAD


• Hurricaine


• Hurricane Spray Kit


• Kank-A Soft Brush


• Larynex


• Miradyne-3


• Mycinette


• Orabase-B


• Oracaine


• Ora film


• Orajel


• OraMagic Plus


• Orasol


• Red Cross Canker Sore


• Thorets


• Trocaine


• Zetts


• Zilactin


• Zilactin-B

In Canada

• Anbesol Extra Strength


• Anbesol Liquid


• Baby Anbesol


• Baby Orajel


• Baby Orajel Liquid


• Maximum Strength Orajel Pm


• Orajel Extra Strength

Available Dosage Forms:

• Liquid


• Gel/Jelly


• Solution


• Lozenge/Troche


• Film


• Lotion


• Ointment


• Powder for Suspension


• Cream


• Tablet, Disintegrating


• Swab


• Spray


• Gum


• Paste

Therapeutic Class: Anesthetic, Local

Chemical Class: Amino Ester

Uses For HAD

Benzocaine lozenges are used to relieve pain and irritation caused by sore throat, sore mouth, or canker sores.

This medicine is available without a prescription; however, your doctor may have special instructions on the proper use and dose for your medical problem.

Before Using HAD

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

No information is available on the relationship of age to the effects of benzocaine lozenges in the pediatric population. Safety and efficacy have not been established in children below 5 years of age.

Geriatric

No information is available on the relationship of age to the effects of benzocaine in geriatric patients.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Infection in or around your mouth or


• Large sores in or around your mouth—The chance of side effects may be increased.

Proper Use of benzocaine

This section provides information on the proper use of a number of products that contain benzocaine. It may not be specific to HAD. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of this medicine, do not use it more often, and do not use it for a longer time than directed. To do so may increase the chance of absorption into the body and the risk of side effects.

This medicine should be used only for problems being treated by your doctor or conditions listed in the package directions. Check with your doctor before using it for other problems, especially if you think that an infection may be present.

Do not use this medicine for more than 2 days without checking first with your doctor.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (lozenges):
  
  • For sore throat and mouth pain:
    
    • Adults, teenagers, and children 5 years of age and older—One lozenge, dissolved slowly in the mouth every 2 hours as needed.
    
    
    • Children younger than 5 years of age—Use is not recommended.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using HAD

If your condition does not improve within 7 days, or if it becomes worse, check with your doctor.

Call your doctor right away if you start to have a severe sore throat or sore throat that occurs with a high fever, headache, nausea, or vomiting. These maybe signs of an infection.

HAD Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

• Headache


• high fever


• nausea


• vomiting


• worsening of pain, redness, swelling, or irritation in or around the mouth

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More HAD resources

• HAD Use in Pregnancy & Breastfeeding
• HAD Support Group
• 6 Reviews for HAD - Add your own review/rating

Compare HAD with other medications

• Anal Itching
• Anesthesia
• Aphthous Ulcer
• Burns, External
• Cold Sores
• Hemorrhoids
• Oral and Dental Conditions
• Pain
• Pruritus
• Sunburn
• Tonsillitis/Pharyngitis

hydrocortisone valerate Topical application

hye-droe-KOR-ti-sone VAL-er-ate

Commonly used brand name(s)

In the U.S.

• Westcort

In Canada

• Hydroval


• Tarocort

Available Dosage Forms:

• Ointment


• Cream

Therapeutic Class: Corticosteroid, Intermediate

Pharmacologic Class: Hydrocortisone

Uses For hydrocortisone valerate

Hydrocortisone valerate topical is used to help relieve redness, itching, swelling, or other discomfort caused by skin conditions. hydrocortisone valerate is a corticosteroid (cortisone-like medicine or steroid).

hydrocortisone valerate is available only with your doctor's prescription.

Before Using hydrocortisone valerate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For hydrocortisone valerate, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to hydrocortisone valerate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of hydrocortisone valerate topical in the pediatric population. However, because of hydrocortisone valerate's toxicity, it should be used with caution. Children and teenagers who must use hydrocortisone valerate should be checked often by their doctor since hydrocortisone valerate topical may be absorbed through the skin and can affect growth or cause other unwanted effects. Safety and effectiveness have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hydrocortisone valerate topical in the elderly.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of hydrocortisone valerate. Make sure you tell your doctor if you have any other medical problems, especially:

• Cushing's syndrome (adrenal gland disorder) or


• Diabetes or


• Hyperglycemia (high blood sugar) or


• Intracranial hypertension (increased pressure in the head)—Use with caution. May make these conditions worse.

• Infection at or near the place of application or


• Large sores, broken skin, or severe injury at the area of application—The chance of side effects may be increased.

Proper Use of hydrocortisone valerate

Use hydrocortisone valerate exactly as directed by your doctor. Do not use it for any other condition without first checking with your doctor. hydrocortisone valerate may cause unwanted effects if it is used too much, because more of it is absorbed into the body through the skin.

Wash your hands with soap and water before and after using hydrocortisone valerate.

Be very careful not to get hydrocortisone valerate in your eyes. Wash your hands after using your finger to apply the medicine. If you accidentally get hydrocortisone valerate in your eyes, flush them with water.

Apply a thin layer of hydrocortisone valerate to the affected area of the skin. Rub it in gently.

Unless otherwise directed by your doctor, do not apply hydrocortisone valerate to open wounds, burns, or broken or inflamed skin.

hydrocortisone valerate should only be used for problems being treated by your doctor. Check with your doctor before using it for other problems, especially if you think that an infection may be present. hydrocortisone valerate should not be used to treat certain kinds of skin infections or serious problems, such as severe burns.

Do not bandage or otherwise wrap the skin being treated unless directed to do so by your doctor.

If your doctor has ordered an occlusive dressing (airtight covering, such as kitchen plastic wrap or a special patch) to be applied over hydrocortisone valerate, make sure you know how to apply it. Since occlusive dressings increase the amount of medicine absorbed through your skin and the possibility of side effects, use them only as directed. If you have any questions about this, check with your doctor.

Do not use hydrocortisone valerate on the face, groin, or underarms unless directed to do so by your doctor.

Dosing

The dose of hydrocortisone valerate will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of hydrocortisone valerate. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For topical dosage forms (cream and ointment):
  
  • For redness, itching, and swelling of the skin:
    
    • Adults—Apply to the affected area of the skin two or three times a day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of hydrocortisone valerate, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using hydrocortisone valerate

It is very important that your doctor check your or your child's progress at regular visits for any problems or unwanted effects that may be caused by hydrocortisone valerate.

If your symptoms do not improve within 2 weeks, or if it become worse, check with your doctor.

After applying hydrocortisone valerate to the skin of your child, watch the child carefully to make sure that he or she does not get any of the medicine in the eyes or mouth. hydrocortisone valerate can cause serious side effects, especially in children, if it gets into the mouth and is swallowed.

Using too much of hydrocortisone valerate or using it for a long time may increase your risk of having adrenal gland problems. The risk is greater for children and for patients who use large amounts for a long time. Talk to your doctor if you or your child have more than one of these symptoms while you are using hydrocortisone valerate: blurred vision; dizziness or fainting; fast, irregular, or pounding heartbeat; increased thirst or urination; irritability; or unusual tiredness or weakness.

Stop using hydrocortisone valerate and check with your doctor right away if you or your child have a skin rash, burning, stinging, swelling, or irritation on the skin.

Avoid using tight-fitting diapers or plastic pants on a child if hydrocortisone valerate is being used on the child's diaper area. Plastic pants and tight-fitting diapers may increase the chance of absorption of the medicine through the skin and the chance of side effects.

Do not use cosmetics or other skin care products on the treated skin areas.

hydrocortisone valerate Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Skin rash, encrusted, scaly, and oozing


• stinging

Less common

• Burning, itching, redness, skin rash, swelling, or soreness at the application site


• cough or hoarseness


• dry skin


• fever or chills


• itching in the genital or other skin areas


• lower back or side pain


• painful or difficult urination


• rash


• rash with flat lesions or small raised lesions on the skin


• skin irritation

Incidence not known

• Blistering, burning, crusting, dryness, or flaking of the skin


• itching, scaling, severe redness, soreness, or swelling of the skin


• redness and scaling around the mouth


• thinning of the skin with easy bruising, especially when used on facial or intertriginous areas

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Diarrhea


• indigestion


• loss of appetite


• nausea or vomiting


• passing of gas


• stomach pain, fullness, or discomfort

Incidence not known

• Acne or pimples


• burning and itching of the skin with pinhead-sized red blisters


• burning, itching, and pain in hairy areas, or pus at the root of the hair


• increased hair growth on the forehead, back, arms, and legs


• lightening of normal skin color


• lightening of treated areas of dark skin


• reddish purple lines on the arms, face, legs, trunk, or groin


• softening of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More hydrocortisone valerate Topical application resources

• Hydrocortisone valerate Topical application Use in Pregnancy & Breastfeeding
• Hydrocortisone valerate Topical application Drug Interactions
• Hydrocortisone valerate Topical application Support Group
• 15 Reviews for Hydrocortisone valerate Topical application - Add your own review/rating

Compare hydrocortisone valerate Topical application with other medications

• Anal Itching
• Aphthous Stomatitis, Recurrent
• Atopic Dermatitis
• Dermatitis
• Eczema
• Gingivitis
• Hemorrhoids
• Proctitis
• Pruritus
• Psoriasis
• Seborrheic Dermatitis
• Skin Rash
• Ulcerative Colitis, Active

Topcare Ibuprofen Oral Suspension

Generic Name: ibuprofen

Dosage Form: oral suspension
Topco Children's Ibuprofen Oral Suspension Drug Facts

Active ingredient (in each 5 mL = 1 teaspoonful)

Ibuprofen 100 mg (NSAID)*

*nonsteroidal anti-inflammatory drug

Purpose

Pain reliever/fever reducer

Uses

temporarily:

• relieves minor aches and pains due to the common cold, flu, sore throat, headache and toothache


• reduces fever

Warnings

Allergy alert: Ibuprofen may cause a severe allergic reaction, especially in people allergic to aspirin. Symptoms may include:

• hives


• facial swelling


• asthma (wheezing)


• shock


• skin reddening


• rash


• blisters

If an allergic reaction occurs, stop use and seek medical help right away.

Stomach bleeding warning: This product contains an NSAID, which may cause severe stomach bleeding.

The chance is higher if your child

• has had stomach ulcers or bleeding problems


• takes a blood thinning (anticoagulant) or steroid drug


• takes other drugs containing prescription or nonprescription NSAIDs (aspirin, ibuprofen, naproxen, or others)


• takes more or for a longer time than directed

Sore throat warning: Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea, and vomiting may be serious. Consult doctor promptly. Do not use more than 2 days or administer to children under 3 years of age unless directed by doctor.

Do not use

• if the child has ever had an allergic reaction to any other pain reliever/fever reducer


• right before or after heart surgery

Ask a doctor before use if

• the stomach bleeding warning applies to your child


• child has a history of stomach problems, such as heartburn


• child has not been drinking fluids


• child has lost a lot of fluid due to vomiting or diarrhea


• child has high blood pressure, heart disease, liver cirrhosis, or kidney disease


• child has asthma


• child is taking a diuretic

Ask a doctor or pharmacist before use if the child is

• under a doctor’s care for any serious condition


• taking any other drug

When using this product

• give with food or milk if stomach upset occurs


• the risk of heart attack or stroke may increase if you use more than directed or for longer than directed

Stop use and ask a doctor if

• child experiences any of the following signs of stomach bleeding:


• feels faint


• vomits blood


• has bloody or black stools


• has stomach pain that does not get better


• the child does not get any relief within first day (24 hours) of treatment


• fever or pain gets worse or lasts more than 3 days


• redness or swelling is present in the painful area


• any new symptoms appear

Keep out of reach of children.

In case of overdose, get medical help or contact a Poison Control Center right away. (1-800-222-1222)

Directions

• this product does not contain directions or complete warnings for adult use


• do not give more than directed


• do not give longer than 10 days, unless directed by a doctor (see Warnings)


• shake well before using


• find right dose on chart. If possible, use weight to dose; otherwise use age.


• use only enclosed measuring cup


• if needed, repeat dose every 6-8 hours


• do not use more than 4 times a day


• replace original bottle cap to maintain child resistance


• wash dosage cup after each use

Dosing Chart
Weight (lb)	Age(yrs)	Dose (teaspoonful or mL)
under 2 years		ask a doctor
24-35 lbs	2-3 years	1 tsp or 5 mL
36-47 lbs	4-5 years	1 ½ tsp or 7.5 mL
48-59 lbs	6-8 years	2 tsp or 10 mL
60-71 lbs	9-10 years	2 ½ tsp or 12.5 mL
72-95 lbs	11 years	3 tsp or 15 mL

Other information

• each teaspoon contains: sodium 2 mg


• do not use if printed neckband is broken or missing


• store at 20-25°C (68-77°F)


• see bottom panel for lot number and expiration date

Inactive ingredients

anhydrous citric acid, butylparaben, D&C red #33, FD&C yellow #6, flavor, glycerin, high fructose corn syrup, hypromellose, polysorbate 80, propylene glycol, purified water, sodium benzoate, sorbitol solution, xanthan gum

Questions or comments?

1-888-423-0139

Principal Display Panel

See New Warnings Information

For Ages 2 to 11

Children’s

Ibuprofen Oral Suspension

100 mg per 5 mL (teaspoonful)

Pain Reliever/Fever Reducer (NSAID)

Lasts up to 8 hours

Alcohol Free

Berry Flavor

Compare to Children’s Motrin® Berry Flavor active ingredient

Children's Ibuprofen Oral Suspension Carton

TOPCARE IBUPROFEN  ibuprofen  suspension

Product Information Product Type HUMAN OTC DRUG NDC Product Code (Source) 36800-897 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength IBUPROFEN (IBUPROFEN) IBUPROFEN 100 mg  in 5 mL

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color ORANGE Score      Shape Size Flavor BERRY Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 36800-897-26 1 BOTTLE In 1 CARTON contains a BOTTLE 1 120 mL In 1 BOTTLE This package is contained within the CARTON (36800-897-26)

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
ANDA	ANDA074937	12/31/1998

Labeler - Topco Associates LLC (006935977)

Revised: 04/2010Topco Associates LLC

More Topcare Ibuprofen Oral Suspension resources

• Topcare Ibuprofen Oral Suspension Side Effects (in more detail)
• Topcare Ibuprofen Oral Suspension Use in Pregnancy & Breastfeeding
• Drug Images
• Topcare Ibuprofen Oral Suspension Drug Interactions
• Topcare Ibuprofen Oral Suspension Support Group
• 51 Reviews for Topcare Ibuprofen - Add your own review/rating

Compare Topcare Ibuprofen Oral Suspension with other medications

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• Headache
• Muscle Pain
• Osteoarthritis
• Pain
• Patent Ductus Arteriosus
• Period Pain
• Rheumatoid Arthritis
• Sciatica
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• Temporomandibular Joint Disorder

Icavex

Icavex may be available in the countries listed below.

Ingredient matches for Icavex

Moxisylyte

Moxisylyte hydrochloride (a derivative of Moxisylyte) is reported as an ingredient of Icavex in the following countries:

• Luxembourg

International Drug Name Search

hydrocortisone, neomycin, and polymyxin B otic

Generic Name: hydrocortisone, neomycin, and polymyxin B otic (HYE droe KOR ti sone, NEE oh MYE sin, POL ee MIX in B)

Brand names: Cort-Biotic, Cortatrigen, Cortatrigen Modified, Cortisporin Otic, Cortomycin, Oti-Sone, Pediotic, ...show all 15 brand names.Drotic, Masporin Otic, Otocort Sterile Solution, Otimar, AK-Spore HC Otic Suspension, Otocort Sterile Suspension, UAD Otic, Antibiotic Ear

What is hydrocortisone, neomycin, and polymyxin B otic?

Hydrocortisone is a steroid. It reduces the actions of chemicals in the body that cause inflammation, redness, and swelling.

Neomycin and polymyxin B are antibiotics that fight bacteria.

The combination of hydrocortisone, neomycin, and polymyxin B otic (for the ears) is used to treat ear infections caused by bacteria.

This medication will not treat a viral infection such as herpes or shingles.

Hydrocortisone, neomycin, and polymyxin B otic may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about hydrocortisone, neomycin, and polymyxin B otic?

You should not use this medication if you are allergic to hydrocortisone, neomycin, or polymyxin B, or if you have a ruptured ear drum, or an ear infection caused by chickenpox, or herpes infection (simplex or zoster).

Before using this medication, tell your doctor if you have herpes (simplex or zoster), chickenpox or small pox, any ear infection that causes blistering, asthma or sulfite allergy, or if you are allergic to an antibiotic similar to neomycin, such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), netilmicin (Netromycin), paromomycin (Humatin, Paromycin), streptomycin, or tobramycin (Nebcin, Tobi).

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Talk with your doctor if your symptoms do not improve after 1 week of using this medication.

Do not use this medication for longer than 10 days in a row unless your doctor tells you to. Long-term use of neomycin may cause damage to your hearing. Stop using this medication and call your doctor at once if you have skin rash, redness, swelling, itching, dryness, scaling, severe burning or stinging, or other irritation in or around the ear. Other serious side effects include new signs of infection, hearing loss, or urinating less than usual or not at all.

What should I discuss with my health care provider before using hydrocortisone, neomycin, and polymyxin B otic?

You should not use this medication if you are allergic to hydrocortisone, neomycin, or polymyxin B, or if you have:

• 
  

  a ruptured ear drum; or

  
  


• 
  

  an ear infection caused by chickenpox, or herpes infection (simplex or zoster).

  
  

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use this medication:

• 
  

  herpes (simplex or zoster);

  
  


• 
  

  chickenpox or small pox;

  
  


• 
  

  any ear infection that causes blistering;

  
  


• 
  

  asthma or sulfite allergy; or

  
  


• 
  

  if you are allergic to an antibiotic similar to neomycin, such as amikacin (Amikin), gentamicin (Garamycin), kanamycin (Kantrex), netilmicin (Netromycin), paromomycin (Humatin, Paromycin), streptomycin, or tobramycin (Nebcin, Tobi).

  
  

FDA pregnancy category C. It is not known whether hydrocortisone, neomycin, and polymyxin B otic ear drops are harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Hydrocortisone and colistin can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication in a child younger than 2 years old.

How should I use hydrocortisone, neomycin, and polymyxin B otic?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Before using this medication, clean and dry your ear canal with sterile cotton.

Shake the ear drops well just before you measure a dose.

This medication is usually given as 4 to 5 drops into the affected ear every 6 to 8 hours. Children may need to use fewer drops. Follow your doctor's instructions about how much medication you should use and how often.

Do not use this medication for longer than 10 days in a row unless your doctor tells you to. Long-term use of neomycin may cause damage to your hearing.

To use the ear drops, first remove the cap from the dropper bottle. Lie down or tilt your head with your ear facing upward. Pull back on your ear gently to open up the ear canal. If giving this medicine to a child, pull down on the earlobe to open the ear canal. Hold the dropper upside down over the ear canal and drop the correct number of drops into the ear.

Do not place the dropper tip into your ear or allow the tip to touch any surface. It may become contaminated.

After using the ear drops, stay lying down or with your head tilted for at least 5 minutes.

As an alternative to dropping the medicine into your ear, you may insert a small piece of cotton into the ear canal and then drop the medicine directly onto the cotton to soak it. Leave the cotton in the ear and keep it moist by adding more of the medication every 4 to 8 hours. Replace the cotton at least every 24 hours. Follow your doctor's instructions about the use of cotton with this medication.

Wipe the ear dropper tip with a clean tissue. Do not wash the tip with water or soap.

Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Talk with your doctor if your symptoms do not improve after 1 week of using this medication.

Store this medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include hearing problems, or urinating less than usual.

What should I avoid while using hydrocortisone, neomycin, and polymyxin B otic?

Avoid getting this medication in your eyes. If this does happen, rinse with water.

Hydrocortisone, neomycin, and polymyxin B otic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  skin rash, redness, swelling, itching, dryness, scaling, or other irritation in or around the ear;

  
  


• 
  

  severe burning, stinging, or other irritation when using the medication;

  
  


• 
  

  new signs of infection;

  
  


• 
  

  hearing loss; or

  
  


• 
  

  urinating less than usual or not at all.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Hydrocortisone, neomycin, and polymyxin B otic Dosing Information

Usual Adult Dose for Otitis Externa:

Solution or suspension: Instill 4 drops into the affected ear(s) 3 to 4 times daily for up to 10 days.

Usual Adult Dose for Otitis Media:

Mastoidectomy infection and fenestration cavity infection:
Suspension: Instill 4 drops into the affected ear(s) 3 to 4 times daily for up to 10 days.

Usual Pediatric Dose for Otitis Externa:

Children:
Solution or suspension: Instill 3 drops into the affected ear(s) 3 to 4 times daily for up to 10 days.

Usual Pediatric Dose for Otitis Media:

Children:
Mastoidectomy infection and fenestration cavity infection:
Suspension: Instill 3 drops into the affected ear(s) 3 to 4 times daily for up to 10 days.

What other drugs will affect hydrocortisone, neomycin, and polymyxin B otic?

It is not likely that other drugs you take orally or inject will have an effect on hydrocortisone, neomycin, and polymyxin B used in the ears. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More hydrocortisone, neomycin, and polymyxin B otic resources

• Hydrocortisone, neomycin, and polymyxin B otic Dosage
• Hydrocortisone, neomycin, and polymyxin B otic Use in Pregnancy & Breastfeeding
• Hydrocortisone, neomycin, and polymyxin B otic Drug Interactions
• Hydrocortisone, neomycin, and polymyxin B otic Support Group
• 0 Reviews for Hydrocortisone, neomycin, and polymyxin B - Add your own review/rating

Compare hydrocortisone, neomycin, and polymyxin B otic with other medications

• Otitis Externa
• Otitis Media

Where can I get more information?

• Your pharmacist can provide more information about hydrocortisone, neomycin, and polymyxin B otic.

Anemia Associated with Chronic Disease Medications

There are currently no drugs listed for "Anemia Associated with Chronic Disease". See Anemia.

Drug List:

Nicoderm

Generic Name: nicotine (Oral route, Transdermal route)

NIK-oh-teen

Commonly used brand name(s)

In the U.S.

• Habitrol


• Nicoderm CQ


• Nicotrol

In Canada

• Nicoderm

Available Dosage Forms:

• Patch, Extended Release

Therapeutic Class: Smoking Cessation Agent

Pharmacologic Class: Cholinergic

Uses For Nicoderm

Nicotine, in a flavored chewing gum, a lozenge, or a skin patch, is used to help you stop smoking. It is used for up to 12 weeks as part of a stop-smoking program. This program may include education, counseling, and psychological support.

As you chew nicotine gum or suck on the nicotine lozenge, nicotine passes through the lining of your mouth and into your blood stream. When you wear a nicotine patch, nicotine passes through your skin into your blood stream. This nicotine takes the place of nicotine that you would otherwise get from smoking. In this way, the withdrawal effects of not smoking are less severe. Then, as your body adjusts to not smoking, the use of the nicotine gum is decreased gradually until use is stopped altogether. For most brands of patches, the strength of the patch you use will be decreased over a few weeks until use is stopped. If you are using the brand of patch that is available in only one strength, use is stopped after the treatment period indicated on the label.

Children, pregnant women, and nonsmokers should not use nicotine gum or patches because of harmful effects.

Nicotine transdermal patches, gum, and lozenges are available without a prescription.

Before Using Nicoderm

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Small amounts of nicotine can cause serious harm in children. Even nicotine patches that have been used still contain enough nicotine to cause problems in children. Although there is no specific information comparing use of nicotine in teenagers with use in other age groups, this medicine is not expected to cause different side effects or problems in nicotine-dependent teenagers than it does in adults.

Geriatric

Nicotine gum, lozenges, and patches have been used in a limited number of patients 60 years of age or older, and have not been shown to cause different side effects or problems in older people than in younger adults.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Clozapine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Dental problems (with gum only) or


• Diabetes, type 1 (sugar diabetes) or


• Heart or blood vessel disease or


• High blood pressure or


• Inflammation of mouth or throat (with gum only) or


• Irritated skin (with patches only) or


• Overactive thyroid or


• Pheochromocytoma (PCC) or


• Stomach ulcer or


• Stroke, recent or


• Temporomandibular (jaw) joint disorder (TMJ) (with gum only)—Nicotine may make the condition worse.

Proper Use of nicotine

This section provides information on the proper use of a number of products that contain nicotine. It may not be specific to Nicoderm. Please read with care.

For patients using the chewing gum:

• Nicotine gum usually comes with patient directions. Read the directions carefully before using this medicine.


• Use nicotine gum exactly as directed on the label. Remember that it is also important to participate in a stop-smoking program during treatment. This may make it easier for you to stop smoking.


• When you feel the urge to smoke, chew one piece of gum very slowly until you taste it or feel a slight tingling in your mouth. Stop chewing, and place (“park”) the chewing gum between your cheek and gum until the taste or tingling is almost gone. Then chew slowly until you taste it again. Continue chewing and stopping (“parking”) in this way for about 30 minutes in order to get the full dose of nicotine.


• Do not chew too fast, do not chew more than one piece at a time, and do not chew more than one piece of gum within an hour. To do so may cause unpleasant side effects or an overdose. Also, slower chewing will reduce the possibility of belching.


• You should not drink acidic beverages, such as citrus fruit juices, coffee, soft drinks, or tea within 15 minutes before or while chewing a piece of gum. The acid will prevent the nicotine from being released from the gum.


• As your urge to smoke becomes less frequent, gradually reduce the number of pieces of gum you chew each day until you are chewing three to six pieces a day. This may be possible within 2 to 3 months.


• Remember to carry nicotine gum with you at all times in case you feel the sudden urge to smoke. One cigarette may be enough to start you on the smoking habit again.


• Using hard sugarless candy between doses of gum may help to relieve any nicotine cravings you may have between doses of gum.

For patients using the lozenge:

• Nicotine lozenges usually come with patient directions. Read the directions carefully before using this medicine.


• Use nicotine lozenges exactly as directed on the label. Remember that it is also important to participate in a stop-smoking program during treatment. This may make it easier for you to stop smoking.


• Do not eat or drink for 15 minutes before using a nicotine lozenge.


• When you feel the urge to smoke, suck one lozenge slowly until it dissolves. Do not bite or chew the lozenge like a hard candy. Do not swallow the lozenge.


• As your urge to smoke becomes less frequent, gradually reduce the number of lozenges you use each day until you are using three to six lozenges a day. This should be possible within 12 weeks.


• Remember to carry nicotine lozenges with you at all times in case you feel the sudden urge to smoke. One cigarette may be enough to start you on the smoking habit again.

For patients using the transdermal system (skin patch):

• Nicotine patches usually come with patient instructions. Read them carefully before using this medicine. Nicotine patches will work only if applied correctly.


• Remember that it is also important to participate in a stop-smoking program during treatment. This may make it easier for you to stop smoking.


• Do not remove the patch from its sealed pouch until you are ready to put it on your skin. The patch may not work as well if it is unwrapped too soon.


• Do not try to trim or cut the adhesive patch to adjust the dosage. Check with your doctor if you think the medicine is not working as it should.


• Apply the patch to a clean, dry area of skin on your upper arm, chest, or back. Choose an area that is not very oily, has little or no hair, and is free of scars, cuts, burns, or any other skin irritations.


• Press the patch firmly in place with the palm of your hand for about 10 seconds. Make sure there is good contact with your skin, especially around the edges of the patch.


• The patch should stay in place even when you are showering, bathing, or swimming. Apply a new patch if one falls off.


• Rinse your hands with plain water after you have finished applying the patch to your skin. Nicotine on your hands could get into your eyes and nose and cause stinging, redness, or more serious problems. Using soap to wash your hands will increase the amount of nicotine that passes through your skin.


• After 16 or 24 hours, depending on which product you are using, remove the patch. Choose a different place on your skin to apply the next patch. Do not put a new patch in the same place for at least 1 week. Do not leave the patch on for more than 24 hours. It will not work as well after that time and it may irritate your skin.


• After removing a used patch, fold the patch in half with the sticky sides together. Place the folded, used patch in its protective pouch or in aluminum foil. Make sure to dispose of it out of the reach of children and pets.


• Try to change the patch at the same time each day. If you want to change the time when you put on your patch, just remove the patch you are wearing and put on a new patch. After that, apply a fresh patch at the new time each day.


• Nicotine patches should be removed from the skin during strenuous exercise. If a patch is left on, too much nicotine may pass through your skin into your blood stream.


• If you are using a 24-hour patch and begin having unusual dreams or disturbed sleep, you may take the patch off before going to bed and put a new one on after you wake up the next morning.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For the oral dosage form (chewing gum):
  
  • To help you stop smoking:
    
    • Adults and teenagers—The usual dose is one piece of chewing gum every one to two hours for six weeks, one piece of chewing gum every two to four hours for three weeks, then one piece of chewing gum every four to eight hours for three weeks. You should not chew more than 24 pieces of gum a day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  


• For the oral dosage form (lozenge):
  
  • To help you stop smoking:
    
    • Adults and teenagers—The usual dose is suck slowly one lozenge until it dissolves every one to two hours for six weeks, suck one lozenge every two to four hours for three weeks, then suck one lozenge every four to eight hours for three weeks. You should not use more than 20 lozenges a day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  


• For the transdermal (stick-on) skin patch:
  
  • To help you stop smoking:
    
    • Adults and teenagers—The dose you receive will be based on your body weight, how often you have the urge to smoke, and the brand and strength of the patch you use. This dose will be provided on the package label.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Nicoderm

Do not smoke during treatment with nicotine gum, lozenges, or patches because of the risk of nicotine overdose.

Nicotine should not be used in pregnancy. If there is a possibility you might become pregnant, you may want to use some type of birth control. If you think you may have become pregnant, stop using this medicine immediately and check with your doctor.

Nicotine products must be kept out of the reach of children and pets. Even nicotine patches that have been used still contain enough nicotine to cause problems in children. If a child chews or swallows one or more pieces of nicotine gum or lozenges, contact your doctor or poison control center at once. If a child puts on a nicotine patch or plays with a patch that is out of the sealed pouch, take it away from the child and contact your doctor or poison control center at once.

For patients using the chewing gum:

• Do not chew more than 24 pieces of gum a day. Chewing too many pieces may be harmful because of the risk of overdose.


• Do not use nicotine gum for longer than 12 weeks. To do so may result in physical dependence on the nicotine. If you feel the need to continue using the gum after 12 weeks, contact your doctor.


• If the gum sticks to your dental work, stop using it and check with your medical doctor or dentist. Dentures or other dental work may be damaged because nicotine gum is stickier and harder to chew than ordinary gum.

For patients using the lozenges:

• Do not use more than 20 lozenges a day. Sucking too many pieces may be harmful because of the risk of overdose.


• Do not use nicotine lozenges for longer than 12 weeks. If you feel the need to continue using the lozenges after 12 weeks, contact your doctor.

For patients using the transdermal system (skin patch) :

• Mild itching, burning, or tingling may occur when the patch is first applied, and should go away within 24 hours. After a patch is removed, the skin underneath it may be red. It should not remain red for more than a day. If you get a skin rash from the patch, or if the skin becomes swollen or very red, call your doctor. Do not put on a new patch. If you become allergic to the nicotine in the patch, you could get sick from using cigarettes or other products that contain nicotine.


• Do not use nicotine patches for longer than 12 weeks if you have stopped smoking. If you feel the need to continue using nicotine patches after 12 weeks, contact your doctor.


• The patch may cause skin burns when used during a procedure called magnetic resonance imaging (MRI). To prevent skin burns, make sure the patch is removed before having an MRI .

Nicoderm Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Injury or irritation to mouth, teeth, or dental work—with chewing gum only

Less common

• High blood pressure

Rare

• Fast or irregular heartbeat


• hives, itching, rash, redness, or swelling of skin

Symptoms of overdose (may occur in the following order)

• Nausea and/or vomiting


• increased watering of mouth (severe)


• abdominal or stomach pain (severe)


• diarrhea (severe)


• pale skin


• cold sweat


• headache (severe)


• dizziness (severe)


• disturbed hearing and vision


• tremor


• confusion


• weakness (severe)


• extreme exhaustion


• fainting


• low blood pressure


• difficulty in breathing (severe)


• fast, weak, or irregular heartbeat


• convulsions (seizures)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Belching—with chewing gum and lozenges


• headache (mild)


• increased appetite


• increased watering of mouth (mild)—with chewing gum only


• jaw muscle ache—with chewing gum only


• redness, itching, and/or burning at site of application of patch—usually stops within 24 hours


• sore mouth or throat—with chewing gum only

Less common or rare

• Abdominal or stomach pain (mild)


• change in sense of taste


• constipation


• coughing (increased)


• diarrhea


• dizziness or lightheadedness (mild)


• drowsiness


• dryness of mouth


• hiccups—with chewing gum and lozenges


• hoarseness—with chewing gum only


• indigestion (mild)


• loss of appetite


• menstrual pain


• muscle or joint pain


• nausea or vomiting (mild)


• passing of gas


• sweating (increased)


• trouble in sleeping or unusual dreams


• unusual irritability or nervousness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Nicoderm side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

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More Nicoderm resources

• Nicoderm Side Effects (in more detail)
• Nicoderm Use in Pregnancy & Breastfeeding
• Nicoderm Drug Interactions
• Nicoderm Support Group
• 8 Reviews for Nicoderm - Add your own review/rating

• Nicotine Professional Patient Advice (Wolters Kluwer)


• Nicotine Monograph (AHFS DI)


• Commit Lozenges MedFacts Consumer Leaflet (Wolters Kluwer)


• Nicorette Prescribing Information (FDA)


• Nicorette Consumer Overview


• Nicorette Gum MedFacts Consumer Leaflet (Wolters Kluwer)


• Nicorette Fruit Chill Prescribing Information (FDA)


• Nicotrol Inhaler Prescribing Information (FDA)


• Nicotrol Inhaler MedFacts Consumer Leaflet (Wolters Kluwer)


• Nicotrol NS Prescribing Information (FDA)


• Nicotrol NS Spray MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Nicoderm with other medications

• Smoking Cessation